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Production of the first ever batch of MVA for a clinical trial using a cell line
June 24, 2015
By: Tim Wright
Editor-in-Chief, Contract Pharma
Complex biologics development and manufacturing specialist ProBioGen recently announced that an investigational vaccine against Ebola virus disease, produced on its proprietary, continuous muscovy duck AGE1.CR.pIX cell line, has proceeded into clinical trials at the Jenner Institute, Oxford University, UK. The vaccine candidate, a modified vaccinia Ankara (MVA) Ebola Zaire vaccine (MVA EBOZ) was produced by Emergent BioSolutions at a 200 liter scale to supply the Phase 1 clinical trial. “Prod...
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